In September 1932, he signed the Poona Pact with MKGandhi abandon separate electorates given the sluggishness of courses by Ramsay MacDonald's Award communal, and instead of accepting equal representation across electorates which has greatly increased the number of seats Reserved. By signing this pact, Ambedkar marked his appearance as leader of the most influential untouchables. From 1932-34, he became a member of the joint committee on constitutional reform India.

A historic Yeola Conversion Conference was held under the Presidentship of Dr.Ambedkar October 13, 1935. There he exhorted the disadvantaged to leave Hinduism and embrace another religion. He also said: "I was born a Hindu, but I am not going to die as a Hindu." These activities have made him unpopular in the mainstream Hindu caste opinion. He was invited by the Jat Pat Todak Mandal Lahore to preside over the conference. Dr. Ambedkar had prepared his historic speech - "The Annihilation of Caste '. But the conference was canceled by the Mandal, on the grounds that Dr. Ambedkar's thoughts were revolutionary. Lastly, he refused to chair and his speech issued in the form book in 1937.

Ambedkar founded the Independent Labour Party and took part in provincial elections held under the Government of India Act, 1935. With the outbreak of the First World War in 1939, Nazi ideology Ambedkar perceived as a direct threat to the freedoms of the Indians. In 1941, he was appointed to the Advisory Committee for the Defence and the following year joined the Board of the viceroy, as a member of the Labour Party. During the same period, he transformed the Labour Party in the independent All India Scheduled Castes Federation.

(Dr. B.R. Ambedkar Center for Biomedical Research (ACBR) is dedicated to research and postgraduate education in Biomedical Sciences. Founded in March 1991, on the occasion of the birth centenary of Baba Saheb Dr. B.R. Ambedkar, the Government of India established an Institute of Biomedical Research at the University of Delhi under the leadership of Prof. Ramesh Chandra, which is rapidly becoming a source of major scientific innovations in the understanding, treatment, and prevention of diseases. The institute also serves as a prototype of postdoctoral training - a scientific centre where young scientists at the start of their research career can gain the skills and insights required in their chosen fields.

In the year 1992, the University finalised the Ordinance relating to the ACBR, which was duly approved by the Hon'ble Visitor - President of India in 1997, the time when ACBR expanded and formalized its educational role by becoming University Maintained Institute for Graduate and Post Graduate Research and a Center for pursuing M.Sc. and M.Sc. - Ph.D. combined degree courses in Biomedical Science, though it was proposed that in the beginning of 21st century, ACBR will be converted into an independent Post Graduate Institution with authority to grant the advance degree, but its charter was amended to make it a part of University of Delhi, to a carefully selected group of gifted students with an opportunity to participate in a tutorial research and educational experience virtually unparalleled in Indian Education.

The first class of M.Sc. - Ph.D. and M.Sc. candidates was admitted in 1998, though the research activities of ACBR have been continuing since 1991 in a historical laboratory in the Department of Chemistry building, where the CSIR and ICMR were born.

The ACBR itself resulted from just a dream - a - dream shared by Prof. Ramesh Chandra, Founder Director, his mentors and students. It was sought to establish a Biomedical Institute that eventually would conglomerate clinical treatment with basic research on diseases - the first of its kind in the Indian University System. The innovative and creative vision of Founder Director and financial support of the Planning Commission, Government of India, University of Delhi. UGC, DST, DBT, CSIR, UNESCO, Polariod Corporation and other agencies led to the establishment of Dr. B.R. Ambedkar Center for Biomedical Research. The foundation stone of ACBR was laid by the Hon'ble Prime Minister of India on March 31st, 1991.

The Institute's first Governing Body was formed in 1996, and an outstanding scholar, a great institution builder and administrator, Padma Bhushan, Late Prof. Gurbakhsh Singh became the first chairperson. Prof. A.R. Kidwai, Former Governor, West Bengal and Bihar and currently Member of Parliament, is the Chairperson of the Governing Body of ACBR.)